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  • Chlorhexidine/ketoconazole/TrizEDTA flush: otic (Mal-A-Ket® Plus) is a liquid antibacterial and antifungal solution used for topical treatment of localized bacterial and yeast infections in dogs and cats. The solution can be used specifically in the ears as a flush treatment.

  • Chlorhexidine/ketoconazole/TrizEDTA flush: topical (Mal-A-Ket® Plus) is a liquid antibacterial and antifungal solution used to manage localized bacterial and yeast infections in dogs and cats. It should only be used topically on the skin or in the ears.

  • Chlorothiazide/hydrochlorothiazide is given by mouth or injection and is used off label to treat nephrogenic diabetes insipidus, high blood pressure, fluid retention, and certain electrolyte imbalances in dogs and cats. Give as directed by your veterinarian.

  • Chloroxylenol topical, also known as PCMX, is a topical antiseptic used on the skin prior to surgery and in wound cleaning in cats, dogs, and exotic species. It has been used to treat bacterial, fungal, and yeast skin infections. It is toxic to aquatic species. All forms are applied topically directly to the skin.

  • Chlorpheniramine maleate is given by mouth and is used off label in cats, dogs, horses, ferrets, and birds to treat allergic conditions or as a mild sedative. Common side effects include sleepiness, although other side effects are possible.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses greater than four months old.

  • Chlortetracycline (brand name Aureomycin®) is a tetracycline antibiotic used to treat certain bacterial infections in food animals, cats, dogs, birds, and some small mammals. Its use may be off label (extra label) depending on species and formulation. Do not use in guinea pigs.

  • Chocolate is toxic to cats. While rarely fatal, chocolate ingestion can result in significant illness. It contains theobromine and caffeine, which cause clinical signs such as an increase in heart rate, blood pressure, agitation, tremors, and seizures. Signs of chocolate poisoning can take several hours to develop and can last for several days.

  • Chocolate is toxic to dogs. While rarely fatal, chocolate ingestion can result in significant illness. It contains theobromine and caffeine, which cause clinical signs such as vomiting, diarrhea, increased thirst, panting or restlessness, and increased heart rate. Signs of chocolate poisoning can take several hours to develop and can last for several days.

  • Cholangitis/cholangiohepatitis syndrome (CCHS) is an inflammatory liver disease. Cholangitis is inflammation of the bile ducts. Cholangiohepatitis is inflammation of the bile ducts, gallbladder, and surrounding liver tissue. This handout outlines clinical signs, diagnosis, treatment, and prognosis.