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Lymphatic tumors are rare in pets. Lymphangiomas are benign and lymphangiosarcomas are malignant and have a moderate-to-high metastatic potential. Patients with lymphatic tumors typically have severe edema or cavity effusions because of lymphatic obstruction and leakage. These types of tumors occur more frequently in young dogs and cats. Treatment usually involves surgical excision and chemotherapy may be used as a follow-up treatment in the case of lymphangiosarcomas.
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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.
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The most common forms of cutaneous lymphoma are epitheliotropic lymphoma and dermal lymphoma. No specific risk factors or causes have been identified in the development of cutaneous lymphoma. Generally, cutaneous lymphoma can appear as various-sized irritated, ulcerated, or infected patches anywhere on the skin, including the gums, nose, or lip margins. These areas may become ulcerated and bleed, or become crusted. Secondary infections are possible. By far, the most common treatment for cutaneous lymphoma is chemotherapy. Unfortunately, the response to treatment, although initially encouraging, is typically short-lived, with gradual return of the tumors.
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Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.
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There are several different types of malignant mammary tumors, with carcinomas being the most common. Carcinomas arise from epithelial (skin) cells, tubules of the mammary glands, or other cells found in the mammary chain. The size of the masses and their appearance may vary, but they are usually firm and nodular. Occasionally, the skin over the mass may ulcerate (open) and bleed, and the affected area may feel warm to the touch and become painful. Detecting and treating these tumors when they are small, and before spread has occurred, will provide your dog with the best chance for long-term control.
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Melanomas are cancerous growths of the cells responsible for pigmentation of the skin. They can develop anywhere on the body but those on the toes carry the highest chance for malignancy. They may be painful and you may notice your pet licking at the affected area. Surgery is often the treatment of choice and may be followed up with radiation or chemotherapy.
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Melioidosis is a bacterial infection that is typically associated with tropical regions. The bacteria that causes melioidosis, Burkholderia pseudomallei, is usually found in soil and water. The clinical signs of this condition, along with transmission, diagnosis, treatment, and prognosis, are outlined in this handout.
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This handout discusses meningitis, an inflammation of the membranes that cover the brain and spinal cord, in dogs. The numerous potential causes, along with the diagnosis, treatment and prognosis of the condition are outlined.
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Meningoencephalitis is a term referring to inflammation of the brain and the surrounding fluid and tissues. Meningoencephalitis of unknown origin is a term used to describe those cases of meningoencephalitis in which MRI and cerebrospinal fluid analysis indicate the disease but diagnosis through histopathological analysis is not possible. Treatment typically involves immunosuppressant drugs, sometimes with the addition of antibiotics. The prognosis depends on several factors, which are also explained in this handout.
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Milbemycin oxime + lufenuron is a heartworm disease preventive that also treats internal parasites (e.g., whipworms, hookworms, and roundworms) and controls flea populations in dogs. Milbemycin oxime + lufenuron is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated; when used off-label at higher doses for treating mites, side effects have been observed. Your veterinarian will advise you on the safety of milbemycin oxime + lufenuron use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.