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  • Spinosad (brand name Comfortis®) is an antiparasitic used to kill adult fleas and to prevent and treat flea infestations in dogs and cats. It may be used off label (extra label) to treat other parasites and in other animals. It comes in an oral tablet form.

  • Spironolactone is given by mouth and is used off label to treat congestive heart failure, fluid accumulation, and other cardiovascular problems.

  • Spironolactone + hydrochlorothiazide is a combination aldosterone antagonist (spironolactone) and thiazide diuretic (hydrochlorothiazide) used to remove excess fluid and salt from the body in cats and dogs. This medication can be used in combination with other drugs to lower blood pressure and for protective effects on the heart muscle. It has also been used in dogs with fluid-up in the abdomen due to liver failure.

  • Spondylosis deformans is a condition that affects the vertebral bones of the spine and is characterized by the presence of bony spurs or osteophytes along the edges of the bones of the spine. Spondylosis deformans is a chronic condition that is associated with aging and most cats show no symptoms. This condition is usually diagnosed from X-rays of the spine. Treatment recommendations depend on the individual cat and whether they are showing any clinical signs, such as pain and difficulty with movement.

  • Spryng intra-articular injectable is an injectable device composed two naturally derived proteins (bovine collagen and elastin) and a carbohydrate (porcine heparin glycan). It is used to help manage non-infectious causes of joint pain in cats, dogs, and horses. When injected into a joint, it creates a spongy matrix that increases joint support and shock absorption, providing a cushioning effect like healthy cartilage. Spryng is to be administered only by trained veterinarians.

  • Squamous cell carcinoma (SCC) is a tumor of the cells that make up the contact or upper layer of the skin. UV light exposure has been described as a developmental factor in people and appears to be associated with its development in cats. Areas affected include the ear tips, skin, toes, or peri-ocular region. Fine needle aspiration or biopsy may be performed for diagnosis. The metastatic rate does not appear overly clear, though staging is always recommended. SCC of the toe can occur as a primary tumor or may have spread from the lung (lung-digit syndrome). Surgery is almost always recommended in any case of SCC; the role of chemotherapy is controversial. Radiation therapy has an excellent response rate in cats with the SCC affecting the nasal planum and may give long-term tumor control.

  • St. John’s wort is an herbal supplement made from the Hypericum perforatum plant. It has traditionally been used for pain, but is also used for depression and anxiety disorders. It may have other anti-inflammatory, antimicrobial, and wound healing effects. It is most commonly used in dogs and cats.

  • Stanozolol (brand names: Winstrol®, Menabol®, Neurabol®, Stanol®, Stromba®, Stombaject®) is an anabolic steroid that no longer commercially marketed in the US. It is currently used off label as a compounded medication to treat weight loss, anemia, poor appetite, and other issues in pet animals (not farmed animals). It may be effective in treating tracheal collapse in dogs.

  • Stasis Breaker is an herbal blend used in Traditional Chinese Veterinary Medicine (TCVM) to reverse blood stagnation and improve circulation in dogs, cats, and horses. It is often recommended for the treatment of cancers that are in the form of a nodule or mass (solid form).

  • Stem cells are unspecialized cells that can renew themselves though cell division. Under certain conditions, they can become a specific tissue or organ cell. Stem cell therapy is the process of placing stem cells from the body into diseased or damaged tissues. This process is often referred to as regenerative medicine.